Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Nigrin b (NGB) fused to a tandem scFv recognizing PDGFR2 and VEGFR2. It contains a His-tag at the C/N terminus for affinity purification. This bispecific immunotoxin can deliver NGB to antigen-specific cells. Then NGB is a lectin and can kill the target cells. The bispecific immunotoxin is designed for the research of Cancers therapy.
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