Name: Recombinant Human Anti-CD3 x Anti-CD19 x Anti-CD22 Trispecific Antibody (Fab-scFv-scFv)
SKU: KN-1025-N1
Rating: 5 (1 reviews)

Recombinant Human Anti-CD3 x Anti-CD19 x Anti-CD22 Trispecific Antibody (Fab-scFv-scFv) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD3 antibody are both extended with two scFv fragments from an anti-CD19 antibody and an anti-CD22 antibody. This TsAb has 1+1+1 antigen-binding valency, it can retarget T cells to tumor cells with higher specificity. It is designed for the research of B cell lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD19 & CD22

Type

Fab-scFv-scFv; Trispecific antibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma; Leukemia

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD19

Gene ID

930

UniProt ID

P15391

Alternative Names

CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4

Target 3

CD22

Gene ID

933

UniProt ID

P20273

Alternative Names

CD22; CD22 molecule; Cluster of differentiation 22; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

See other bsAb targets related to "CD3"

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See other bsAb targets related to "CD22"

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Recombinant Human Anti-CD3 x Anti-CD19 x Anti-CD22 Trispecific Antibody (Fab-scFv-scFv) (CAT#: KN-1025-N1)

Specifications

Targets

Customer Reviews and Q&As