Name: Recombinant Human Anti-CD3 x Anti-CD28 x Anti-PSMA Trispecific Antibody (Single-chain triplebody)
SKU: KN-1025-N15
Rating: 5 (1 reviews)

Recombinant Human Anti-CD3 x Anti-CD28 x Anti-PSMA Trispecific Antibody (Single-chain triplebody) is designed to be expressed as a single chain with three scFv units for CD3, CD28 and PSMA. It contains a His-tag at the C/N terminus for affinity purification. This TsAb has 1+1+1 antigen-binding valency, it provides two signals to activate T cells and recruit them to PSMA+ tumor cells. It is designed for the research of Prostate cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD28 & PSMA

Type

Single-chain triplebody; Trispecific antibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Prostate cancer

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 3

PSMA

Gene ID

2346

UniProt ID

Q04609

Alternative Names

PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALA; FOLH1; folate hydrolase 1; NAALAdase; Glutamate carboxypeptidase 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD3 x Anti-CD28 x Anti-PSMA Trispecific Antibody (Single-chain triplebody) (CAT#: KN-1025-N15)

Specifications

Targets

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