Name: Recombinant Human Anti-CD3 x Anti-CD40 x Anti-HER2 Trispecific Antibody (Single-chain triplebody)
SKU: KLN-1125-LN27
Rating: 5 (1 reviews)

Recombinant Human Anti-CD3 x Anti-CD40 x Anti-HER2 Trispecific Antibody (Single-chain triplebody) is designed to be expressed as a single chain with three scFv units for CD3, CD40 and HER2. It contains a His-tag at the C/N terminus for affinity purification. This TsAb has 1+1+1 antigen-binding valency, it provides two signals to activate T cells and recruit them to HER2+ tumor cells. It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD40 & HER2

Type

Single-chain triplebody; Trispecific antibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD40

Gene ID

958

UniProt ID

P25942

Alternative Names

CD40 molecule; CD40; p50; Bp50; Cluster of differentiation 40; CDW40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5

Target 3

HER2

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

See other bsAb targets related to "CD40"

See other bsAb targets related to "CD3"

See other bsAb targets related to "HER2"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CD3 x Anti-CD40 x Anti-HER2 Trispecific Antibody (Single-chain triplebody) (KLN-1125-LN27). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-CD3 x Anti-CD40 x Anti-HER2 Trispecific Antibody (Single-chain triplebody) (CAT#: KLN-1125-LN27)

Specifications

Targets

Customer Reviews and Q&As