Name: Anti-VEGF x Anti-4-1BB Bispecific aptamer (RNA/RNA)
SKU: KN-0825-JL5
Rating: 5 (1 reviews)

Anti-VEGF x Anti-4-1BB Bispecific aptamer (RNA/RNA) consists of an anti-VEGF DNA aptamer and a 2'FY modified dimeric anti-4-1BB RNA aptamer. It has 1+2 antigen-binding valency for VEGF and 4-1BB respectively. This bispecific aptamer (BsApt) can costimulate T cells to engender potent antitumor immunity. It is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

VEGF & 4-1BB

Type

Bispecific Aptamer

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Targets

Target 1

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Target 2

4-1BB

Gene ID

3604

UniProt ID

Q07011

Alternative Names

CD137; Cluster of Differentiation 137; 4-1BB; 4-1BB Receptor; ILA; Induced by Lymphocyte Activation; T-cell Antigen 4-1BB Homolog; CDw137; IMD109; 4-1BB ligand receptor; Tumor necrosis factor receptor superfamily member 9; T-cell antigen ILA

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

See other bsAb targets related to "4-1BB"

See other bsAb targets related to "VEGF"

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Anti-VEGF x Anti-4-1BB Bispecific aptamer (RNA/RNA) (CAT#: KN-0825-JL5)

Specifications

Targets

Customer Reviews and Q&As