Mouse Anti-CSPG4 DNA-encoded mAb (Clone 7G4E5), pVAX1(DMAb-0596-WJ)

DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics. This product is the plasmid containing an encoded Mouse anti-CSPG4 DMAb (Clone 7G4E5) sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.


Specifications


Target
CSPG4
Target Species
Human
DMAb Host
Mouse
DMAb Immunogen
Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli
DMAb Cross Reactivity
Human
DMAb Isotype
IgG1
DMAb Clone
7G4E5
Vector Name
pVAX1
Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
Vector Promoter
CMV
Vector Tag or Fusion
Untagged
Delivery Method
Transfection
Cloning Method
Restriction Enzyme ⁄ MCS
Constitutive or Inducible System
Constitutive
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Target


Entrez Gene ID
UniProt ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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