Mouse Anti-MUC1 DNA-encoded mAb (CBFYM-2786), pVAX1(DMAb-2486-FY)

DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics. This product is the plasmid containing an encoded Mouse Anti-MUC1 DMAb (CBFYM-2786) sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.


Specifications


Target
MUC1
Target Species
Human
DMAb Host
Mouse
DMAb Immunogen
Full length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell
DMAb Cross Reactivity
Human, Dog, Monkey
DMAb Isotype
IgG2a
DMAb Clone
CBFYM-2786
Vector Name
pVAX1
Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
Vector Promoter
CMV
Vector Tag or Fusion
Untagged
Delivery Method
Transfection
Cloning Method
Restriction Enzyme ⁄ MCS
Constitutive or Inducible System
Constitutive
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Target


Entrez Gene ID
UniProt ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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USA: 1-631-381-2994
Europe: 44-207-097-1828
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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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