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Mouse Anti-PMEL DNA-encoded mAb (Clone CBXS-4068), pVAX1 (DMAb-1769-CQ)

DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics. This product is the plasmid containing an encoded Mouse anti-PMEL DMAb (Clone CBXS-4068) sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • PMEL
  • DMAb Host
  • Mouse
  • DMAb Immunogen
  • Human recombinant protein fragment corresponding to amino acids 25-467 of human SILV (NP_008859)
  • DMAb Cross Reactivity
  • Human
  • DMAb Isotype
  • IgG1
  • DMAb Clone
  • CBXS-4068
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Target

  • Entrez Gene ID
  • 6490

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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