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Anti-PRDM10ᵐᵘᵗ (S1050F) T cell receptor (1A/1003), pCDTCR1 (TCR-YC1035)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-PRDM10ᵐᵘᵗ (S1050F) T cell receptor (TCR) is constructed for the engineering of T cell to target PRDM10ᵐᵘᵗ (S1050F) (TYLPSAWNF) restricted by HLA-A*24:02. The T cells are genetically modified through transduction with a lentiviral vector expressing PRDM10ᵐᵘᵗ (S1050F)-specific T cell receptor.

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Details

  • Target
  • PRDM10ᵐᵘᵗ (S1050F)
  • Epitope
  • TYLPSAWNF
  • Format
  • Non-Modified TCR
  • Allele
  • HLA-A*24:02
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • 1A/1003
  • Host Species
  • Human

Target

  • Introduction
  • The expression level of PRDM10 in Ma-Mel-86a and −86f was comparable to the reference melanocytes, whereas it was lower in Ma-Mel-86b and −86c. This gene was only mutated in Ma-Mel-86a and 37% of the reads aligning to the mutated position carried the SNS.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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