The vector of anti-TYR chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TYR. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-TYR antibody linked to 4-1BB (CD137) and CD3ζ signaling domains. And the vector product was designed for the treatment of Melanoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|TCR-L119||Murinized (from Human) anti-TYR (YMDGTMSQV) T Cell Receptor[Cysteine-modiﬁed], pMSGV1|
|CAR-YJ933||Anti-TYR (OCA1/812) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-YJ436||Anti-TYR (TRSN1-1) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-YJ432||Anti-TYR (2A2-F4) h(41BB-CD3ζ) CAR, pCDCAR1|
|DMAb-0435-YJ||Mouse Anti-TYR DNA-encoded mAb (Clone TRSN1-1), pVAX1|
|TCR-L257||Human anti-Tyrosinase T cell receptor (di111), pCDTCR1|
|VP-TCR-C573||Lenti-Tyrosinase T cell receptor (Cysteine-modiﬁed) Viral Particle|
|TCR-L116Z||Human anti-tyrosinase (aa369-377) T cell receptor, pCDTCR1|
|DMAb-0433-YJ||Mouse Anti-TYR DNA-encoded mAb (Clone SPM360), pVAX1|
|DMAb-0431-YJ||Mouse Anti-TYR DNA-encoded mAb (Clone 2A2-F4), pVAX1|
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