Get a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Overview
Acute lymphoblastic leukemia (ALL) accounts for almost one third of all kinds of cancers in children within the age ranging from 3 to 5 and affects slightly more boys than girls. This disease results from numerous of redundant immature white blood cell (WBC), which crowds out normal WBC, leading the immune system into a dangerous situation of fighting microbe invasion. The exact causes to this disease are still not clear, however, exposure to radiation or benzene, smoking, drinking more than two cups of coffee during pregnancy may increase the risk of childhood ALL. Some other factors such as genetic conditions or viuses infection also play roles in the origination of this blood tumor.
Signs, symptoms and treatments
Symptoms of ALL include frequent infections, fever, pale skin, loss of appetite, shortness of breath, bone pain, lumps in the neck and small red spots under the skin. In ALL clinical treatments, conventional chemotherapy, radiation therapy or stem cell transplantation always followed with serious side effects or rejection reaction. Gene-engineered-methods have developed a heartening road via redirecting T cells to target tumors antigens more effectively to perform the anti-tumor function of T cells.
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NEWSLETTER
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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