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Overview
Hodgkin lymphoma is a type of lymphoma cancer that arises in the lymphatic system and causes affected lymph nodes to get larger, which results from the abnormally reproduction of cells in the lymphatic system. Hodgkin lymphoma forms tumors in the lymph nodes or can also spread to other organs, like spleen, liver, bone marrow or lungs. Each year. about 6000 new cases of Hodgkin lymphoma are diagnosed in America, with around 10% to 15% of which are diagnosed in children and adolescent teenagers, more commonly in boys than in girls. Both Epstein-Barr virus infecton and HIV infection are linked to the cause of this disease. A person who has a weakened immune system, or a close relative (especially a brother or sister) who is a Hodgkin lymphoma patient, is thought to have a higher risk of developing this disease.
Signs, symptoms and treatments
Symptoms of Hodgkin lymphoma vary from one case to another, which may include: painless swollen lymph nodes in the neck or armpit, extreme fatigue, loss of appetite, weight loss, fever, heavy night sweats, itchy skin and enlargement of the liver or spleen. In order to kill as many cancer cells as possible, chemotherapy may be used alone or combined with radiation therapy depending on the stage and subtype of Hodgkin lymphoma. The stem cell transplant therapy may be also an option if the disease reemerges.
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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