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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Characteristics of T cells
T cells or T lymphocytes are a population of white blood cells that play a protection function from infections and disease in the body, consisting of several specialized T cell types to perform their own specific immune function against pathogens. As a part of the adaptive immunity system, T cells carry out specific and targeted defenses against foreign pathogens, such as allergens, bacteria, and some endogenous cells.
Fig.1 Development of γδ and αβ T lymphocytes in the thymus.1
Functions of T Cells
T lymphocytes recognize foreign antigens by initiating and generating targeted inflammatory responses. T cells recognize foreign antigens through hyper-variable T cell receptor (TCR) specificity, and the TCR will only trigger T cell activation upon exposure to its unique antigen. Additionally, it needs to be stressed that the recognizing process requires the major histocompatibility complex (MHC) presented on the surface of antigen-presenting cells to counter the original antigen for presentation.
When activated, T cells undergo clonal expansion, and there will be a great many identical T cells with the same TCR specificity. T cells will also release a mass of cytokines in this process, which signals to other immune cells that the foreign antigen has been recognized. On the one hand, T cells can directly kill the infected cells, on the other hand, T cells can also recruit other immune cells to help expand the attack. After the threat is repelled, regulatory T cells reduce the inflammatory response while triggering apoptosis in T cells that are no longer needed. Some T cells are retained as memory T cells to ensure a rapid and efficient response in the event of re-exposure.
The Application Fields of T Cells
By studying the unique composition and function of different T cells at the macro (large population) and micro (individual) levels, we can help accelerate research in many areas.
T Cells at Creative Biolabs
Different T cell subpopulations have specific functions related to life stages. Molecular, phenotypic, and functional analysis of these diverse T-cell subpopulations will greatly facilitate research related to disease processes, including autoimmune diseases, inflammatory diseases, and cancer. To facilitate the global customer project process, Creative Biolabs provides a variety of T cell subsets with high purity and viability. All of the relevant biological samples were obtained from IRB-consented donors. Meanwhile, Creative Biolabs is committed to offering customized service and cell products to every customer.
Here are some hot products that you can browse to find a suitable product for your project. If you are interested in our cell products, please contact us at your convenience.
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