The vector of anti-CSPG4 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CSPG4. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-CSPG4 antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of CSPG4-positive solid tumors including melanoma, breast carcinoma, HNSCC and mesothelioma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC180||Lenti-HMW-MAA CAR (scFv-CD28-OX40-CD3ζ, 225.28S) Viral Particle|
|CAR-T-2-M318-BZ||Anti-HMW-MAA scFv h(41BB-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC618||Lenti-CSPG4 CAR (scFv-CD28-CD3ζ, 763.74) Viral Particle|
|CAR-T-1-M318-Z||Anti-HMW-MAA scFv h(CD3ζ) CART, pCDCAR1|
|VP-CAR-LC169||Lenti-HMW-MAA CAR (scFv-CD28, 225.28S) Viral Particle|
|CAR-T-2-M318-2G||Anti-HMW-MAA scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC170||Lenti-HMW-MAA CAR (scFv-FcεRIγ, 225.28S) Viral Particle|
|CAR-LC134||Anti-CSPG4 (763.74) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC816||Lenti-CSPG4 CAR (scFv-CD28-CD3ζ, 149.53) Viral Particle|
|VP-CAR-LC172||Lenti-HMW-MAA CAR (scFv-CD28-FcεRIγ, 225.28S) Viral Particle|
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