The vector of anti-FRA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human FRA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-FRA antibody linked to CD3ζ and CD27 signaling domains. And the vector product was designed for the treatment of ovarian cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ154||Anti-FRα (MOv19) h(CD3ζ) CAR, pCDCAR1|
|CAR-MZ155||Anti-FRα (MOv19) h(CD137-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC532||Lenti-FRA CAR (scFv-ICOS-CD3ζ, MOv19) Viral Particle|
|VP-CAR-LC649||Lenti-FRA CAR (scFv-CD3ζ, C4) Viral Particle|
|VP-CAR-LC512||Lenti-FRA CAR (scFv-CD27-CD3ζ , C4) Viral Particle|
|VP-CAR-LC850||Lenti-FRα (Folate receptor-alpha) CAR (scFv-CD137-CD3ζ, MOv19) Viral Particle|
|VP-CAR-LC849||Lenti-FRα (Folate receptor-alpha) CAR (scFv-CD3ζ, MOv19) Viral Particle|
|CAR-LC164||Anti-FRA (C4) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC648||Lenti-FRA CAR (scFv-CD28-CD3ζ, C4) Viral Particle|
|CAR-LC040||Anti-FRA (MOv19) h(ICOS-CD3ζ) CAR, pCDCAR1|
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