The vector of anti-FRB chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human FRB. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-FRB antibody linked to CD3ζ signaling domain. And the vector product was designed for the treatment of acute myeloid leukemia.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC652||Lenti-FRB CAR (scFv-CD28-CD3ζ, m923) Viral Particle|
|CAR-LC166||Anti-FRB (m909) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC653||Lenti-FRB CAR (scFv-CD3ζ, m923) Viral Particle|
|VP-CAR-LC651||Lenti-FRB CAR (scFv-CD3ζ, m909) Viral Particle|
|CAR-LC167||Anti-FRB (m909) h(CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC650||Lenti-FRB CAR (scFv-CD28-CD3ζ, m909) Viral Particle|
|CAR-LC168||Anti-FRB (m923) h(CD28-CD3ζ) CAR, pCDCAR1|
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