The vector of anti-HLA-A2/WT1Db126 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HLA-A2/WT1Db126. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-HLA-A2/WT1Db126 antibody linked to FcγRIγ signaling domains. And the vector product was designed for the treatment of Human cancers.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ109||Anti-HLA-A2 (BB7.2) h(CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC808||Lenti-HLA-A2 CAR (scFv-CD3ζ, BB7.2) Viral Particle|
|CAR-MZ124||Anti-HLA-A2/WT1Db126 (F3) h(CD28- FcγRIγ) CAR, pCDCAR1|
|VP-CAR-LC809||Lenti-HLA-A2 CAR (scFv-CD28-CD3ζ, BB7.2) Viral Particle|
|VP-CAR-LC822||Lenti-HLA-A2-WT1Db126 CAR (scFv-FcγRIγ, F2) Viral Particle|
|VP-CAR-LC823||Lenti-HLA-A2-WT1Db126 CAR (scFv-FcγRIγ, F3) Viral Particle|
|VP-CAR-LC810||Lenti-HLA-A2 CAR (scFv-41BB-CD3ζ, BB7.2) Viral Particle|
|CAR-MZ111||Anti-HLA-A2 (BB7.2) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-MZ110||Anti-HLA-A2 (BB7.2) h(CD28-CD3ζ) CAR, pCDCAR1|
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