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Lenti-CD22 CAR (scFv-28ζ, m971)-VP (VP-CAR-LC642)

The ready-to-use lentiviral particles of Lenti-CD22 CAR (scFv-28ζ, m971)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (m971)-CD28-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

  • Type of Therapeutics
  • Chimeric Antigen Receptor
  • Target
  • CD22
  • Expression Cassette
  • scFv (m971)-CD28-CD3ζ
  • Clone
  • m971
  • Promotor
  • EF1a
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Acute lymphoblastic leukemia

Target

  • Introduction
  • CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD24 include Refractory Hematologic Cancer and Refractory Hairy Cell Leukemia. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Marrs and Innate Immune System. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC1.
  • Alternative Names
  • CD22 Molecule; CD22 Antigen; Sialic Acid-Binding Ig-Like Lectin 2; B-Lymphocyte Cell Adhesion Molecule; T-Cell Surface Antigen Leu-14; SIGLEC-2;

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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