Lenti-CD33 CAR (scFv-28εRIγ, CAMPATH-1H)-VP(VP-CAR-LC100)

The ready-to-use lentiviral particles of Lenti-CD33 CAR (scFv-28εRIγ, CAMPATH-1H)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (CAMPATH-1H)-CD28-FcεRIγ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD33
Expression Cassette
scFv (CAMPATH-1H)-CD28-FcεRIγ
Clone
CAMPATH-1H
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Acute myeloid leukemia (AML)

Target


Introduction
CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells
Alternative Names
CD33; CD33 molecule; p67; SIGLEC3; SIGLEC-3; AML; acute myeloid leukaemia; leukaemia; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; CAMPATH-1H
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Leukemia

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CONTACT US

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-097-1828

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