The vector of anti-MUC16 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human MUC16. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-MUC16 antibody linked to CD137 and CD3ζ signaling domains. And the vector product was designed for the treatment of Ovarian cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ193||Anti-MUC16 (4H11) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC820||Lenti-MUC16 CAR (scFv-41BB-CD3ζ, 4H11) Viral Particle|
|VP-CAR-LC884||Lenti-MUC16 CAR (scFv-CD28-41BB-CD3ζ, 4H11) Viral Particle|
|VP-CAR-LC881||Lenti-MUC16 CAR (scFv-CD3ζ, 4H11) Viral Particle|
|CAR-MZ192||Anti-MUC16 (4H11) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC818||Lenti-MUC16 CAR (scFv-CD28-CD3ζ, 4H11) Viral Particle|
|CAR-MZ191||Anti-MUC16 (4H11) h(CD3ζ) CAR, Pcdcar1|
|VP-CAR-LC819||Lenti-MUC16 CAR (scFv-CD137-CD3ζ, 4H11) Viral Particle|
|CAR-MZ194||Anti-MUC16 (4H11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
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