The vector of anti-CD123 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD123. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD123 antibody linked to CD4 transmembrane domain and FcεRIγ signaling domains. And the vector product was designed for the treatment of acute myeloid leukaemia (AML).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-M306-8Z||Anti-CD123 scFv h(CD8-CD3ζ) CART, pCDCAR1|
|CAR-T-2-M306-2G||Anti-CD123 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC281||Lenti-CD123 CAR (scFv-CD28, 7G3 ) Viral Particle|
|VP-CAR-LC282||Lenti-CD123 CAR (scFv-FcεRIγ, 7G3 ) Viral Particle|
|CAR-T-1-M306-2||Anti-CD123 scFv h(CD28) CART, pCDCAR1|
|VP-CAR-LC283||Lenti-CD123 CAR (scFv-CD3ζ, 7G3 ) Viral Particle|
|CAR-T-1-M306-Z||Anti-CD123 scFv h(CD3ζ) CART, pCDCAR1|
|VP-CAR-LC657||Lenti-CD123 CAR (scFv-41BB-CD3ζ) Viral Particle|
|VP-CAR-LC658||Lenti-CD123 CAR (scFv-41BB-CD3ζ, Klon43) Viral Particle|
|VP-CAR-LC291||Lenti-CD123 CAR (scFv-CD28-41BB-CD3ζ, 7G3 ) Viral Particle|
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