The vector of anti-CS1 chimeric antigen receptor(CAR) is constructed for the engineering of NK cells to target Human CS1. The NK cells are genetically modified through transduction with a Lentiviral vector expressing scFv of anti-CS1 antibody linked to b2c and CD3-zeta signaling domains. And the vector product was designed for the treatment of multiple myeloma (MM).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-L349-BZ||Anti-CSH1 scFv h(41BB-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC162||Lenti-CSH1 CAR (scFv-CD4-FcεRIγ, 162.1) Viral Particle|
|CAR-NK-1-M329-G||Anti-CS1 scFv h(FcεRIγ) CARNK, pCDCAR1|
|VP-CAR-LC158||Lenti-CSH1 CAR (scFv-FcεRIγ, 162.1) Viral Particle|
|VP-CAR-LC168||Lenti-CSH1 CAR (scFv-CD28-OX40-CD3ζ, 162.1) Viral Particle|
|VP-CAR-LC165||Lenti-CSH1 CAR (scFv-41BB-CD3ζ, 162.1) Viral Particle|
|VP-CAR-LC161||Lenti-CSH1 CAR (scFv-CD28-CD3ζ, 162.1) Viral Particle|
|VP-CAR-LC160||Lenti-CSH1 CAR (scFv-CD28-FcεRIγ, 162.1) Viral Particle|
|CAR-NK-2-M329-BG||Anti-CS1 scFv h(CD28-FcεRIγ) CARNK, pCDCAR1|
|VP-CAR-LC167||Lenti-CSH1 CAR (scFv-CD28-41BB-CD3ζ, 162.1) Viral Particle|
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