The vector of anti-FRα chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human FRα. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-FRα antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of ovarian cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC443||Lenti-AE1 CAR (scFv-CD4-CD3ζ, MOv19) Viral Particle|
|VP-CAR-LC444||Lenti-AE1 CAR (scFv-CD8-CD3ζ, MOv19) Viral Particle|
|CAR-T-1-M313-2||Anti-FRα scFv h(CD28) CART, pCDCAR1|
|VP-CAR-LC448||Lenti-AE1 CAR (scFv-CD28-OX40-CD3ζ, MOv19) Viral Particle|
|CAR-T-2-M313-2G||Anti-FRα scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC441||Lenti-AE1 CAR (scFv-CD28-CD3ζ, MOv19) Viral Particle|
|CAR-T-2-M313-2Z||Anti-FRα scFv h(CD28-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC447||Lenti-AE1 CAR (scFv-CD28-41BB-CD3ζ, MOv19) Viral Particle|
|VP-CAR-LC440||Lenti-AE1 CAR (scFv-CD28-FcεRIγ, MOv19) Viral Particle|
|CAR-T-2-M313-8Z||Anti-FRα scFv h(CD8-CD3ζ) CART, pCDCAR1|
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