The vector of anti-HBV S protein chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HBV S protein. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-HBV S protein antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of cirrhosis, hepatocellular carcinoma (HCC), liver cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC453||Lenti-HBV CAR (scFv-CD28-CD3ζ, S 26) Viral Particle|
|VP-CAR-LC450||Lenti-HBV CAR (scFv-FcεRIγ, S 26) Viral Particle|
|CAR-T-2-M319-4G||Anti-HBV S protein scFv h(CD4-FcεRIγ) CART, pCDCAR1|
|CAR-T-2-M319-2G||Anti-HBV S protein scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC452||Lenti-HBV CAR (scFv-CD28-FcεRIγ, S 26) Viral Particle|
|CAR-T-2-M319-4Z||Anti-HBV S protein scFv h(CD4-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC460||Lenti-HBV CAR (scFv-CD28-OX40-CD3ζ, S 26) Viral Particle|
|VP-CAR-LC454||Lenti-HBV CAR (scFv-CD4-FcεRIγ, S 26) Viral Particle|
|CAR-T-2-M319-CZ||Anti-HBV S protein scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-T-3-M319-2BZ||Anti-HBV S protein scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1|
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