The vector of anti-HER2 chimeric antigen receptor(CAR) is constructed for the engineering of T cell to target human HER2. The T cell is genetically modified through transduction with a lentiviral vector expressing anti-HER2 VHH linked to CD137 (4-1BB) and CD3-zeta signaling domains. And the vector product was designed for the treatment of breast cancer, hepatocellular liver carcinoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ136||Anti-ErbB2 (N29) h(CD28-FcγR) CAR, pCDCAR1|
|TCR-C098Z||Murinized anti-HER2 T cell receptor (HER2-2), pCDTCR1|
|CAR-MZ135||Anti-ErbB2 (L96) h(CD28-FcγR) CAR, pCDCAR1|
|VP-CAR-LC832||Lenti-ErbB2 CAR (scFv-CD28-FcγR, L96) Viral Particle|
|CAR-T-2-M550-4G||Anti-HER2 VHH h(CD4-FcεRIγ) CAR, [T]|
|VP-CAR-LC830||Lenti-ErbB2 CAR (scFv-CD28-CD3ζ, N29) Viral Particle|
|CAR-NK-2-M331-BZ||Anti-ErbB2 scFv h(41BB-CD3ζ) CARNK, pCDCAR1|
|CAR-T-2-L337-CZ||Anti-ErbB2 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-NK-2-M331-4G||Anti-ErbB2 scFv h(CD4-FcεRIγ) CARNK, pCDCAR1|
|VP-TCR-C137||Lenti-Her2 T cell receptor (G8) Viral Particle|
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