The vector of anti-HIV chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HIV. The T cells are genetically modified through transduction with a lentiviral vector expressing CD4 linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of AIDS.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-1-L408-G||HIV h(FcεRIγ) CAR, [T]|
|CAR-T-2-L408-4Z||HIV h(CD4-CD3ζ) CAR, [T]|
|CAR-T-2-L408-2Z||HIV h(CD28-CD3ζ) CAR, [T]|
|CAR-T-2-L408-BZ||HIV h(41BB-CD3ζ) CAR, [T]|
|CAR-T-2-L408-4G||HIV h(CD4-FcεRIγ) CAR, [T]|
|CAR-T-3-L408-2BZ||HIV h(CD28-41BB-CD3ζ) CAR, [T]|
|CAR-T-3-L408-2XZ||HIV h(CD28-OX40-CD3ζ) CAR, [T]|
|CAR-T-2-L408-CZ||HIV h(b2c-CD3ζ) CAR, [T]|
|CAR-T-1-L408-2||HIV h(CD28) CAR, [T]|
|CAR-T-2-L408-8Z||HIV h(CD8-CD3ζ) CAR, [T]|
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