The vector of anti-HMW-MAA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HMW-MAA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-HMW-MAA antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of metastatic melanoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC817||Lenti-CSPG4 CAR (scFv-CD28-CD3ζ, G71.1) Viral Particle|
|VP-CAR-LC173||Lenti-HMW-MAA CAR (scFv-CD28-CD3ζ, 225.28S) Viral Particle|
|VP-CAR-LC816||Lenti-CSPG4 CAR (scFv-CD28-CD3ζ, 149.53) Viral Particle|
|VP-CAR-LC172||Lenti-HMW-MAA CAR (scFv-CD28-FcεRIγ, 225.28S) Viral Particle|
|VP-CAR-LC888||Lenti-CSPG4 CAR (scFv-CD3ζ, 763.74) Viral Particle|
|CAR-MZ200||Anti-CSPG4 (763.74) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-MZ118||Anti-CSPG4 (G71.1) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC177||Lenti-HMW-MAA CAR (scFv-41BB-CD3ζ, 225.28S) Viral Particle|
|CAR-T-2-M318-2Z||Anti-HMW-MAA scFv h(CD28-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC176||Lenti-HMW-MAA CAR (scFv-CD8-CD3ζ, 225.28S) Viral Particle|
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