The vector of anti-HMW-MAA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HMW-MAA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-HMW-MAA antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of metastatic melanoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC179||Lenti-HMW-MAA CAR (scFv-CD28-41BB-CD3ζ, 225.28S) Viral Particle|
|DMAb-1790-FY||Mouse Anti-CSPG4 DNA-encoded mAb (CBFYM-1055), pVAX1|
|CAR-T-3-M318-2BZ||Anti-HMW-MAA scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1|
|DMAb-0594-WJ||Rat Anti-CSPG4 DNA-encoded mAb (Clone CBWJN-1076), pVAX1|
|DMAb-1792-FY||Mouse Anti-CSPG4 DNA-encoded mAb (CBFYM-1057), pVAX1|
|CAR-WJ2888||Anti-CSPG4 (7G4E5) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC888||Lenti-CSPG4 CAR (scFv-CD3ζ, 763.74) Viral Particle|
|DMAb-0596-WJ||Mouse Anti-CSPG4 DNA-encoded mAb (Clone 7G4E5), pVAX1|
|CAR-YC1092||Anti-CSPG4 (132.38) h(scFv-CD28-CD3ζ) CAR, pCDCAR1|
|CAR-WFY1791||Anti-CSPG4 (CBFYM-1056) h(41BB-CD3ζ) CAR, pCDCAR1|
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