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ALPL

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This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY061 Anti-ALPL h(41BB-CD3ζ) CAR, pCDCAR1 Baboon, Human, Mandrill, Monkey Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY063 Anti-ALPL h(41BB-CD3ζ) CAR, pCDCAR1 Human, Marmoset, Monkey Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1701 Anti-ALPL h(CD28-CD3ζ) CAR, pCDCAR1 Baboon, Human, Mandrill, Monkey Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1703 Anti-ALPL h(CD28-CD3ζ) CAR, pCDCAR1 Human, Marmoset, Monkey Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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