CD8

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Associated Disease
  • Breast cancer

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-T-1-L348-2 T cell First CA-8 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-L348-G T cell First CA-8 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-L348-Z T cell First CA-8 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-L348-2G T cell Second CA-8 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-L348-2Z T cell Second CA-8 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-L348-4G T cell Second CA-8 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-L348-4Z T cell Second CA-8 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-L348-8Z T cell Second CA-8 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-L348-BZ T cell Second CA-8 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-L348-CZ T cell Second CA-8 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-L348-2BZ T cell Third CA-8 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-L348-2XZ T cell Third CA-8 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC133 CA-8 Lentivirus First scFv (CA-8)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC134 CA-8 Lentivirus First scFv (CA-8)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC135 CA-8 Lentivirus First scFv (CA-8)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC136 CA-8 Lentivirus Second scFv (CA-8)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC137 CA-8 Lentivirus Second scFv (CA-8)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC138 CA-8 Lentivirus Second scFv (CA-8)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC139 CA-8 Lentivirus Second scFv (CA-8)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC140 CA-8 Lentivirus Second scFv (CA-8)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC141 CA-8 Lentivirus Second scFv (CA-8)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC142 CA-8 Lentivirus Second scFv (CA-8)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC143 CA-8 Lentivirus Third scFv (CA-8)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC144 CA-8 Lentivirus Third scFv (CA-8)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

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Australia
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