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DCTN2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0357 Anti-DCTN2 (25/Dynactin p50) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 25/Dynactin p50 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0358 Anti-DCTN2 (2B9A5) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 2B9A5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0359 Anti-DCTN2 (2G7) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 2G7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1257 Anti-DCTN2 (25/Dynactin p50) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 25/Dynactin p50 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1258 Anti-DCTN2 (2B9A5) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 2B9A5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1259 Anti-DCTN2 (2G7) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 2G7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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