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ESPL1

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Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009).
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ0782 Anti-ESPL1 (XJ11-1B12) h(41BB-CD3ζ) CAR, pCDCAR1 Human XJ11-1B12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0783 Anti-ESPL1 (CBXS-3480) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3480 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0784 Anti-ESPL1 (CBXS-3481) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3481 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0785 Anti-ESPL1 (CBXS-3532) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3532 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0786 Anti-ESPL1 (XJ11-4D7) h(41BB-CD3ζ) CAR, pCDCAR1 Human XJ11-4D7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4206 Anti-ESPL1 (XJ11-1B12) h(CD28-CD3ζ) CAR, pCDCAR1 Human XJ11-1B12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4207 Anti-ESPL1 (CBXS-3480) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3480 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4208 Anti-ESPL1 (CBXS-3481) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3481 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4209 Anti-ESPL1 (CBXS-3532) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3532 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4210 Anti-ESPL1 (XJ11-4D7) h(CD28-CD3ζ) CAR, pCDCAR1 Human XJ11-4D7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0364 Anti-ESPL1 (XJ11-4D7) h(41BB-CD3ζ) CAR, pCDCAR1 Human XJ11-4D7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0365 Anti-ESPL1 (CBFYE-0168) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0168 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0366 Anti-ESPL1 (CBFYE-0263) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0263 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0367 Anti-ESPL1 (CBFYE-1236) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-1236 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3617 Anti-ESPL1 (XJ11-4D7) h(CD28-CD3ζ) CAR, pCDCAR1 Human XJ11-4D7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3618 Anti-ESPL1 (CBFYE-0168) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0168 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3619 Anti-ESPL1 (CBFYE-0263) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0263 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3620 Anti-ESPL1 (CBFYE-1236) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-1236 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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