Fibroblast activation protein (FAP)

Fibroblast activation protein alpha (FAP) also called FAPA is a melanoma membrane-bound gelatinase, which encoded by the FAP gene in human. This protein a homodimeric integral membrane gelatinase belonging to the serine protease family. FAP is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds and malignant cells of bone and soft tissue sarcomas. Therefore, this protein is associated with epithelial cancers, breast cancer, colorectal cancer, skin cancer, pancreatic carcinomas, hepatocellular carcinomas, ovarian carcinomas and gastrointestinal carcinomas.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC223 T cell Second 73.3 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC224 T cell Second 73.3 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ141 T cell Second MO36 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ142 T cell Second MO36 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ143 T cell Third MO36 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ182 T cell Second mAb 73.3 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC698 73.3 Lentivirus Second scFv (73.3)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC699 73.3 Lentivirus Second scFv (73.3)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC838 MO36 Lentivirus Second scFv (MO36)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC839 MO36 Lentivirus Second scFv (MO36)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC840 MO36 Lentivirus Third scFv (MO36)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC876 mAb 73.3 Lentivirus Second scFv (mAb73.3)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON