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GCDH

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The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY1091 Anti-GCDH (3E9BA3BF5) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human 3E9BA3BF5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1092 Anti-GCDH (CBLG1-2671) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLG1-2671 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2731 Anti-GCDH(3E9BA3BF5) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human 3E9BA3BF5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2732 Anti-GCDH(CBLG1-2671) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLG1-2671 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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