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EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
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EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also called CD213A2, CT19, IL-13R, IL13BP, is a membrane bound protein that in humans is encoded by the IL13RA2 gene. This protein is a component of the cell surface receptor. Compared to IL-13Rα1, IL-13Rα2 play an opposite role as a potent IL13 antagonist. IL-13Rα2 is infected in the disease of glioblastoma multiforme and malignant glioma though the pathway of immune system and Akt signaling.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-T-2-M401-BZ | IL13Rα2 h(41BB-CD3ζ) CAR, [T] | Human | Human | scFv-41BB-CD3ζ | Lentiviral | T cell | |||
| CAR-T-2-M401-CZ | IL13Rα2 h(b2c-CD3ζ) CAR, [T] | Human | Human | scFv-b2c-CD3ζ | Lentiviral | T cell | |||
| CAR-T-1-M401-2 | IL13Rα2 h(CD28) CAR, [T] | Human | Human | scFv-CD28 | Lentiviral | T cell | |||
| CAR-T-3-M401-2BZ | IL13Rα2 h(CD28-41BB-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | |||
| CAR-T-2-M401-2Z | IL13Rα2 h(CD28-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-CD3ζ | Lentiviral | T cell | |||
| CAR-T-2-M401-2G | IL13Rα2 h(CD28-FcεRIγ) CAR, [T] | Human | Human | scFv-CD28-FcεRIγ | Lentiviral | T cell | |||
| CAR-T-3-M401-2XZ | IL13Rα2 h(CD28-OX40-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-OX40-CD3ζ | Lentiviral | T cell | |||
| CAR-T-1-M401-Z | IL13Rα2 h(CD3ζ) CAR, [T] | Human | Human | scFv-CD3ζ | Lentiviral | T cell | |||
| CAR-T-2-M401-4Z | IL13Rα2 h(CD4-CD3ζ) CAR, [T] | Human | Human | scFv-CD4-CD3ζ | Lentiviral | T cell | |||
| CAR-T-2-M401-4G | IL13Rα2 h(CD4-FcεRIγ) CAR, [T] | Human | Human | scFv-CD4-FcεRIγ | Lentiviral | T cell | |||
| CAR-T-2-M401-8Z | IL13Rα2 h(CD8-CD3ζ) CAR, [T] | Human | Human | scFv-CD8-CD3ζ | Lentiviral | T cell | |||
| CAR-LC235 | Anti-IL13Rα2 (m47) h(-CD28-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv--CD28-CD3ζ | Retroviral | T cell | ||
| CAR-LC236 | Anti-IL13Rα2 (m47) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv-CD28-41BB-CD3ζ | Retroviral | T cell | ||
| CAR-LC283 | Anti-IL13Rα2 h(CD3ζ) Ligand-based CAR, pCDCAR1 | Human | Human | IL13-CD3ζ | Retroviral | T cell | |||
| CAR-LC284 | Anti-IL13Rα2 h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 | Human | Human | IL13-CD28-CD3ζ | Retroviral | T cell | |||
| CAR-MZ148 | Anti-IL13Rα2 (scFv47) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv-41BB-CD3ζ | Retroviral | T cell | ||
| CAR-MZ238 | Anti-IL13Rα2, IL13 mutein E13K h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13K-CD28-CD3ζ | Retroviral | T cell | ||||
| CAR-MZ239 | Anti-IL13Rα2, IL13 mutein E13Y h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13Y-CD28-CD3ζ | Retroviral | T cell | ||||
| CAR-MZ240 | Anti-IL13Rα2, IL13 mutein E13K.K105R h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13K.K105R-CD28-CD3ζ | Retroviral | T cell | ||||
| CAR-MZ241 | Anti-IL13Rα2, IL13 mutein E13Y.K105R h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13Y.K105R-CD28-CD3ζ | Retroviral | T cell |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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