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ILF2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WJ0813 Anti-ILF2 (CBWJN-0905) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJN-0905 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0814 Anti-ILF2 (6F1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6F1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ3105 Anti-ILF2 (CBWJN-0905) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJN-0905 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ3106 Anti-ILF2 (6F1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6F1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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