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KIFAP3

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The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY968 Anti-KIFAP3 (CBLY1-091) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLY1-091 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY969 Anti-KIFAP3 (CBLY1-092) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLY1-092 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY970 Anti-KIFAP3 (7C9F2) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human 7C9F2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2608 Anti-KIFAP3(CBLY1-091) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLY1-091 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2609 Anti-KIFAP3(CBLY1-092) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBLY1-092 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2610 Anti-KIFAP3(7C9F2) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human 7C9F2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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