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MAN1B1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY1845 Anti-MAN1B1 (CBFYM-1361) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1361 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1846 Anti-MAN1B1 (CBFYM-1362) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1362 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5098 Anti-MAN1B1 (CBFYM-1361) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1361 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5099 Anti-MAN1B1 (CBFYM-1362) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1362 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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