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MAPK1/MAPK2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases , act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY1955 Anti-MAPK1/MAPK2 (CBFYM-1575) h(41BB-CD3ζ) CAR, pCDCAR1 Bird, Mouse, Rat, Human CBFYM-1575 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5208 Anti-MAPK1/MAPK2 (CBFYM-1575) h(CD28-CD3ζ) CAR, pCDCAR1 Bird, Mouse, Rat, Human CBFYM-1575 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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