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MCM6

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY2068 Anti-MCM6 (1/MCM6) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1/MCM6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2069 Anti-MCM6 (CBFYM-1908) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1908 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2070 Anti-MCM6 (CBFYM-1909) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYM-1909 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5321 Anti-MCM6 (1/MCM6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1/MCM6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5322 Anti-MCM6 (CBFYM-1908) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1908 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5323 Anti-MCM6 (CBFYM-1909) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYM-1909 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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