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P4HB

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY0620 Anti-P4HB (CBFYE-1571) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-1571 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0621 Anti-P4HB (CBFYE-1572) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-1572 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3873 Anti-P4HB (CBFYE-1571) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-1571 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3874 Anti-P4HB (CBFYE-1572) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-1572 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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