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PCDHB1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

PCDHB1 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0821 Anti-PCDHB1 (1H4) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 1H4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0822 Anti-Pcdhb1 (S144-32) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Mouse S144-32 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1721 Anti-PCDHB1 (1H4) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 1H4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1722 Anti-Pcdhb1 (S144-32) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Mouse S144-32 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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