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PSEN1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. It is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0197 Anti-PSEN1 (APS18) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human APS18 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1097 Anti-PSEN1 (APS18) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human APS18 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1073 PSEN1 (NCSTN Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human PSEN1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2473 PSEN1 (NCSTN Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human PSEN1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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