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SCARB2

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The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2028 Anti-SCARB2 (JL2) h(41BB-CD3ζ) CAR, pCDCAR1 Human JL2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2029 Anti-SCARB2 (CBXS-2724) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2724 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5452 Anti-SCARB2 (JL2) h(CD28-CD3ζ) CAR, pCDCAR1 Human JL2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5453 Anti-SCARB2 (CBXS-2724) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-2724 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ176 Anti-Scarb2 (1K53) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse 1K53 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ676 Anti-Scarb2 (1K53) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse 1K53 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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