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SF1

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This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2278 Anti-SF1 (CBXS-5899) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5899 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2279 Anti-SF1 (CBXS-4525) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-4525 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2280 Anti-SF1 (CBXS-2201) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-2201 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5702 Anti-SF1 (CBXS-5899) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5899 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5703 Anti-SF1 (CBXS-4525) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-4525 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5704 Anti-SF1 (CBXS-2201) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-2201 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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