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TP53BP1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TP53BP1 is a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. TP53BP1 plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ330 Anti-TP53BP1 (1B9) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1B9 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ331 Anti-TP53BP1 (2H6) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2H6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ830 Anti-TP53BP1 (1B9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1B9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ831 Anti-TP53BP1 (2H6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2H6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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