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TP63

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TP63 is a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in TP63 are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ333 Anti-TP63 (XHM540) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM540 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ833 Anti-TP63 (XHM540) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM540 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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