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TXNRD2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TXNRD2 belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. TXNRD2 is a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It plays a role as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ427 Anti-TXNRD2 (25B3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 25B3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ428 Anti-TXNRD2 (3F2-E12-F10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3F2-E12-F10 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ429 Anti-TXNRD2 (7B2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 7B2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ927 Anti-TXNRD2 (25B3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 25B3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ928 Anti-TXNRD2 (3F2-E12-F10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3F2-E12-F10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ929 Anti-TXNRD2 (7B2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7B2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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