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ZCCHC8

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

ZCCHC8 (Zinc Finger CCHC-Type Containing 8) is a Protein Coding gene which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WJ2129 Anti-ZCCHC8 (CBWJZ-057) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJZ-057 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4421 Anti-ZCCHC8 (CBWJZ-057) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJZ-057 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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