The vector of anti-TSLPR chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TSLPR. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-TSLPR antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of B-lineage acute lymphoblastic leukemia (B-ALL).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ094||Anti-TSLPR (3G11) h(CD8-41BB-CD3ζ) CAR, pCDCAR1|
|CAR-LC189||Anti-TSLPR (3G11) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC801||Lenti-TSLPR CAR (scFv-CD3ζ, 3G11) Viral Particle|
|VP-CAR-LC668||Lenti-TSLPR CAR (scFv-41BB-CD3ζ, 3G11) Viral Particle|
|VP-CAR-LC802||Lenti-TSLPR CAR (scFv-CD8-41BB-CD3ζ, 3G11) Viral Particle|
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