Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | C-C chemokine receptor type 2 |
| Gene Name | CCR2 |
| Uniprot | P41597 (Human); P51683 (Mouse) |
| Synonym | CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; C-C chemokine receptor type 2; MCP-1 receptor |
| Background | CCR-2 (alternatively known as monocyte chemoattractant protein 1 receptor, MCP-1-R) is a G protein-coupled receptor, which is encoded by the CCR2 gene in human. Interaction with the C-C chemokine receptor 2 (CCR2) is mediated by a specific ligand set: CCL2, CCL7, CCL13, and the antimicrobial peptides DEFB106A/DEFB106B. Significantly, CCR2 expression transcends the hematopoietic compartment—being observed on macrophages, for example—to include diverse non-hematopoietic populations such as endothelial cells, fibroblasts, and mesenchymal stem cells. Its principal established function involves mediating the CCL2-directed chemotaxis of monocytes. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX476 | NativeExtract™ Human CCR2 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPVLP-006 | MemDX™ Recombinant Human CCR2b Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MP1331J | MemDX™ Membrane Protein Human CCR2 (C-C motif chemokine receptor 2) for Antibody Discovery | E.colicell-free | Full length | Detergent |
| S01YF-0423-KX527 | MemDX™ Membrane Protein Human CCR1 (1-34aa) Expressed in HEK293, C-Human Fc tag | HEK293 cells | Partial | N/A |
| Please for more products or customization | ||||
W****am: The CCR2 protein we received from Creative Biolabs was delivered promptly and in perfect condition. We were impressed with their professionalism and the overall quality of their products.
08/ Aug/2023
E**a: The technical support team at Creative Biolabs was very knowledgeable and helpful in answering our questions about the CCR2 protein. Their expertise was invaluable to our research.
03/Apr/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers sCCR2 gene therapy development services. Gene therapy approaches employing soluble C-C chemokine receptor 2 (sCCR2) demonstrate considerable potential for attenuating joint inflammation and mitigating cartilage degradation, thereby modulating osteoarthritis (OA) progression. Mechanistically underpinning this strategy is a specifically engineered fusion protein construct; this molecule integrates sCCR2 with a 20-amino acid segment derived from the third extracellular (E3) domain of the CCL2 receptor.
Creative Biolabs offers gene editing services. The advent of gene editing technologies presents a compelling avenue for therapeutic intervention targeting the CCR2 gene. This methodology harnesses the precision of guide RNAs (gRNAs) to direct the Cas9 nuclease to defined genomic loci, thereby enabling highly specific modifications to the genetic code.
Creative Biolabs offers comprehensive and innovative services to drive the development of CCR2 cell therapy. Please for more services.
Creative Biolabs offers CCR2-overexpressing mesenchymal stem cells construction services. An innovative strategy within CCR2-based cell therapy entails the genetic engineering of mesenchymal stem cells (MSCs) to overexpress the CCR2 receptor. This modification aims specifically to augment the targeted homing of these MSCs towards sites of tissue injury.
Creative Biolabs offers CCR2-overexpressing carrier-free nanotechnology research services. A novel nanotechnology-based approach involves using CCR2-overexpressing macrophage membranes for cancer treatment. It targets cancer cells via the CCR2-CCL2 axis and induces ferroptosis.
Creative Biolabs is the industry leader in conducting difficult and unique membrane protein preparation studies through a variety of validated strategies, which ensure reliable results. The preparation method and protocols are fine-tuned to meet the specific requirements demanded by each client of the different scientific investigation. Please feel free to for expert support.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
